| LAST DOSE BEFORE BRONCHOSCOPY | TIME TO RESTART MEDICATIONS AFTER BRONCHOSCOPY WITH BIOPSIES | |
| Heparin SubQ | No Need to stop | Not applicable |
| Enoxaparin 1mg/Kg SubQ BID | Omit the evening dose prior to procedure day (last dose 24 hours prior to procedure) | > 12 hours |
| Enoxaparin 1.5mg/Kg SubQ QD | > 24 hours | > 12 hours |
| Warfarin (Coumadin) | 5 days (confirm INR < 1.5) | immediately |
| Heparin IV | > 4 hours (check PTT) | > 4 hours (no bolus) |
| Fondaparinux (Arixtra) | 4 days | > 12 hours |
| Rivaroxaban (Xarelto) | 3 days | > 24 hours |
| Apixaban (Eliquis) | 3 days | > 12 hours |
| Edoxaban (Syvasa) | 3 days | |
| Streptokinase (Local) | No Need to stop | |
| Alteplase (Local) | No Need to stop | |
| Alteplase (Systemic) | 10 days | 10 days |
| Streptokinase (Systemic) | 10 days | 10 days |
| Urokinase (Systemic) | 10 days | 10 days |
| Aspirin | No Need to stop | |
| NSAID | No Need to stop | |
| ASA/Dipyridamole (Aggrenox) | > 24 hours | immediately |
| Abciximab (Reopro) | > 48 hours (check platelet/PTT) | > 4 hours |
| Cilostazol (Pletal) | 3 days | > 6 hours |
| Clopidogrel (Plavix) | 5 days | > 6 |
| Eptifibatide (Integrilin) | 8 hours (check Platelet/PTT) | > 4 hours |
| Tirofiban (Aggrastat) | 8 hours (check Platelet/PTT) | > 4 hours |
| Ticagrelor (Brilinta) | 5 days | > 6 hours |
| Cangrelor (Kangreal) | > 4 hours | > 2 hours |
| Ticlopidine (Ticlid) | 5 days | immediately |
| Prasugrel (Effient) | 7 days | > 8 hours |
| Argatroban (Acova) | > 4 hours (check PTT) | > 2 hours |
| Dagitraban (Pradaxa) | 5 days | > 6 hours |
| Bevalirudin (Angiomax) | > 10 hours | > 4 hours |
| Desirudin (Revasc) | > 10 hours | > 4 hours |
| Lepirudin (Refludan) | > 10 hours | > 4 hours |
| Time to resume anticoagulants COULD BE CHANGED by physician |
Regional Anesthesia and Antithrombotic Agents.: Recommendations of the European Society of Anesthesiology. European Journal of Anaesthesiology 2010; 27: 999-1015